Editorial educational content. Specialist review is not claimed; consult the original references and limitations.
Definition and context
A combination of chromatographic separation and mass spectrometry.
What to check
Connect chromatographic peaks to observed ions, considering ionization, charge and acquisition conditions.
Interpretation
Observed mass alone does not fully determine purity.
Sources and verification scope
Therapeutic peptides: current applications and future directions ↗
Wang et al. · Signal Transduction and Targeted Therapy
Source details (original language)
- Scope
- Review of therapeutic peptide development
- Document section
- Introduction; production, modification and applications
- Limitations
- Historical review, not validation of products or batches. More than 80 approved drugs is a 2022 literature statement.
- Claim verification date
- 2026-09-09
Related reading
HRMS
Mass spectrometry capable of distinguishing signals close in mass-to-charge ratio.
Read details →Molecular weight
A quantity related to molecular composition; the convention and unit must be stated.
Read details →